Published by BBC NEWS - 5th March 2022

The parents of a five-year-old girl have said they believe she is the only child in the world to have a rare genetic condition.

Isla was born with mandibuloacral dysplasia, which causes features of premature ageing.

The family have said they do not know what her future holds and have used social media to raise awareness of her condition.

Prof Pradeep Vasudevan, consultant clinical geneticist at Leicester’s Hospitals, said: “Isla’s condition is very rare – fewer than 50 cases have been recorded in medical literature.

“Because of this, many cases most likely go misdiagnosed or undiagnosed making it difficult to determine the true frequency of mandibuloacral dysplasia in the general population.”

Video journalist: Chris Waring

Follow BBC East Midlands on Facebook, Twitter, or Instagram. Send your story ideas to




Tel: +44 (0) 141 946 6482

Address: Healthcare Skills Training International Ltd
West of Scotland Science Park
Block 7, Kelvin Campus
Glasgow G20 0SP